Naltrexone 1mg/1ml Oral Solution
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Description
Naltrexone is an opioid receptor antagonist traditionally used at higher doses for the management of opioid or alcohol dependence. When used at much lower doses, such as 1mg per ml, it is commonly referred to as Low-Dose Naltrexone (LDN).
In low doses, naltrexone is thought to work by temporarily blocking opioid receptors, which may stimulate the body’s natural endorphin production and help regulate immune and inflammatory responses. For this reason, LDN is often prescribed off-label for conditions such as autoimmune disorders, chronic pain, fatigue-related conditions, and inflammatory illnesses.
This oral solution formulation allows for flexible dosing and accurate dose titration, particularly for patients who require very low or gradually increasing doses. Naltrexone 1mg/1ml oral solution is supplied on prescription following clinical assessment.
Warnings
Naltrexone may not be suitable for everyone. Do not take this medicine if you:
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Are currently using opioid-based pain relief
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Are dependent on opioids
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Have acute hepatitis or severe liver disease
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Are allergic to naltrexone or any of the ingredients
Speak to your prescriber before taking Naltrexone if you:
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Have liver or kidney disease
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Have a history of substance dependence
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Are pregnant or breastfeeding
Stopping opioids suddenly before starting naltrexone can cause withdrawal symptoms. Always follow medical advice.
Directions
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Take Naltrexone exactly as prescribed by your doctor
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Measure the dose carefully using an oral syringe
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Usually taken once daily, often in the evening
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Can be taken with or without food
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Do not exceed the prescribed dose
If a dose is missed, take the next dose at the usual time. Do not take a double dose.
Ingredients
Active ingredient:
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Naltrexone hydrochloride 1mg per 1ml
Other ingredients may include:
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Purified water
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Preservatives and flavouring agents (depending on formulation)
Always check the patient information leaflet for full ingredient details, especially if you have allergies.
Side Effects
Like all medicines, Naltrexone can cause side effects, although not everyone will experience them.
Common side effects:
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Sleep disturbances or vivid dreams
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Headache
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Nausea
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Fatigue
Less common side effects:
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Dizziness
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Anxiety
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Digestive discomfort
Seek medical advice immediately if you experience:
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Signs of liver problems such as yellowing of the skin or eyes
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Severe abdominal pain
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Allergic reactions including swelling of the face, lips, or throat
FAQs
What is Naltrexone 1mg/1ml used for?
At this strength, it is commonly prescribed as Low-Dose Naltrexone (LDN) for immune modulation, inflammation, and chronic conditions.
Is this the same as standard Naltrexone tablets?
It contains the same active ingredient but at a much lower dose and in liquid form, allowing more precise dosing.
How long does LDN take to work?
Some patients notice improvements within a few weeks, while others may take several months to experience benefits.
Can Naltrexone oral solution be taken long term?
Yes, many patients take LDN long term under medical supervision.
Can I take Naltrexone if I use opioid painkillers?
No. Naltrexone blocks opioid receptors and should not be taken with opioid-containing medicines.
